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Tab. Bizoran 5/40 mg

SKU: Cs24957

Amlodipine Besilate + Olmesartan Medoxomil
5 mg+40 mg
Beximco Pharmaceuticals Ltd.

Original price was: ৳ 20.00.Current price is: ৳ 18.00.

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Description

Indication:
Indicated for the treatment of hypertension (high blood pressure) to reduce the risk of cardiovascular events, particularly in patients who require combination therapy.

Pharmacology, Dosage & Administration:
Bisoprolol is a selective beta-1 blocker that reduces heart rate, cardiac output, and blood pressure.
Olmesartan is an angiotensin II receptor blocker (ARB) that inhibits vasoconstriction and lowers blood pressure.
Typical dose: One tablet once daily, with or without food, as prescribed by a physician.

Interaction:
Increased risk of hypotension with diuretics or other antihypertensive agents.
May interact with NSAIDs (reducing antihypertensive effect) and lithium (increased toxicity risk).
Caution when combined with insulin or oral hypoglycemics due to enhanced hypoglycemic effects.

Contraindications:
Hypersensitivity to bisoprolol, olmesartan, or any component of the formulation.
Severe bradycardia, heart block, or cardiogenic shock (bisoprolol-related).
Severe renal artery stenosis or pregnancy (olmesartan-related).

Side Effects:
Common: Dizziness, fatigue, headache, hypotension, and nausea.
Rare: Bradycardia, elevated potassium levels, and kidney dysfunction.

Pregnancy & Lactation:
Contraindicated in pregnancy due to risk of fetal toxicity (from olmesartan).
Caution during lactation; consult a healthcare provider before use.

Precautions & Warnings:
Monitor for electrolyte imbalances, especially potassium.
Caution in patients with renal impairment, diabetes, or heart failure.
Avoid abrupt discontinuation of bisoprolol to prevent rebound hypertension or heart issues.

Overdose Effects:
Symptoms may include severe hypotension, bradycardia, dizziness, and acute renal failure.
Supportive and symptomatic treatment is recommended.

Therapeutic Class:
Beta-Blocker and Angiotensin II Receptor Blocker (ARB) Combination

Storage Conditions:
Store below 30°C in a cool, dry place, away from direct light and moisture.
Keep out of reach of children.

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