Tab. Rosuva 20 mg

Ingredients:
Each tablet contains:
Rosuvastatin Calcium equivalent to 20mg of Rosuvastatin
Excipients: As per standard formulation (e.g., lactose, microcrystalline cellulose, magnesium stearate)

Direction of Use:
Take exactly as prescribed by the physician.
Swallow the tablet whole with a glass of water, with or without food.
Preferably taken at the same time each day.

Indication:
Hyperlipidemia (high cholesterol)
Mixed dyslipidemia
Hypertriglyceridemia
Primary prevention of cardiovascular disease in patients at high risk
Familial hypercholesterolemia (heterozygous or homozygous)

Pharmacology:
Rosuvastatin is an HMG-CoA reductase inhibitor (statin) that works by blocking the enzyme responsible for cholesterol synthesis in the liver. This leads to a reduction in total cholesterol, LDL-C (bad cholesterol), triglycerides, and a mild increase in HDL-C (good cholesterol).

Category:
Lipid-lowering agent
Statin (HMG-CoA reductase inhibitor)

Dosage & Administration:
Adults: Usual starting dose is 10mg once daily.
Rosuva 20mg may be prescribed in moderate to severe hyperlipidemia or as per clinical response.
Dosage may be adjusted at intervals of 4 weeks or more.
Maximum recommended dose: 40mg per day (in selected patients only).
Dose adjustment required in patients with renal impairment or Asian ethnicity.

How to Use:
Do not break or crush the tablet.
Do not exceed the prescribed dose.
Continue even if you feel well; it controls cholesterol, not cures it.
Regular follow-up and lipid profile monitoring are advised.

Interaction:
May interact with:
Cyclosporine
Warfarin
Antacids (containing aluminum or magnesium)
Fibrates
Niacin
Protease inhibitors (used in HIV treatment)
Avoid excessive alcohol intake

Contraindications:
Hypersensitivity to Rosuvastatin or any excipient
Active liver disease
Unexplained persistent elevations of liver enzymes

Pregnancy and lactation
Severe renal impairment

Product Technical Details:
Strength: 20mg
Form: Film-coated tablet
Packaging: Typically in blister packs (e.g., 10 tablets per strip)

Side Effects:
Common:
Headache
Muscle pain (myalgia)
Abdominal pain
Nausea
Weakness
Serious (rare):
Rhabdomyolysis
Liver enzyme abnormalities
Renal impairment
Allergic reactions

Pregnancy & Lactation:
Contraindicated.
Rosuvastatin may cause harm to the fetus.
Should not be used during pregnancy or breastfeeding.

Precautions & Warnings:
Use with caution in patients with:
Liver dysfunction
History of muscle disorders
Alcohol use disorder
Hypothyroidism
Monitor liver enzymes and CK levels periodically.
Report unexplained muscle pain or weakness immediately.

Overdose Effects:
No specific antidote.
Symptomatic and supportive treatment recommended.
Monitor liver function and CK levels in suspected overdose.

Therapeutic Class:
Lipid-regulating drugs
Statins (HMG-CoA reductase inhibitors)

Storage Conditions:
Store below 30°C in a dry place.
Protect from light and moisture.
Keep out of reach of children.

Disclaimer:
This information is provided for educational purposes only and is not a substitute for professional medical advice. Always consult your doctor or pharmacist before starting or stopping any medication. Manufacturer is not responsible for misuse or adverse outcomes from off-label use.