Cap. Maxrin 0.4 mg

Description

Maxrin 0.4 mg contains Tamsulosin Hydrochloride (0.4 mg), an alpha-1 adrenergic receptor blocker used to treat Benign Prostatic Hyperplasia (BPH). It helps relax the muscles in the prostate and bladder neck, improving urine flow and reducing symptoms of BPH.

Ingredients:
Tamsulosin Hydrochloride (0.4 mg)

Direction of Use:
Take once daily, preferably 30 minutes after the same meal each day.
Swallow the capsule whole with water; do not crush or chew.

Indication:
Treatment of Benign Prostatic Hyperplasia (BPH) symptoms, including:
Difficulty urinating
Weak urine stream
Frequent urination (especially at night)

Pharmacology, Dosage & Administration:
Pharmacology:
Tamsulosin selectively blocks alpha-1 adrenergic receptors in the prostate, bladder neck, and urethra, leading to smooth muscle relaxation and improved urine flow.

Dosage & Administration:
Usual dose: 0.4 mg once daily after food.
Dosage may be adjusted based on patient response.

Interaction:
May interact with antihypertensives, causing a drop in blood pressure.
Increased risk of hypotension with PDE5 inhibitors (e.g., Sildenafil).
Caution with CYP3A4 inhibitors (e.g., Ketoconazole, Erythromycin).

Contraindications:
Hypersensitivity to Tamsulosin.
Severe liver impairment.
Patients with a history of orthostatic hypotension.

Side Effects:
Common: Dizziness, headache, abnormal ejaculation, nasal congestion.
Serious: Severe hypotension, priapism (rare but serious).

Precautions & Warnings:
Caution in patients with low blood pressure or a history of fainting.
Should not be used in women and children.
Can cause Intraoperative Floppy Iris Syndrome (IFIS) during cataract surgery—inform the surgeon before surgery.

Overdose Effects:
Symptoms include severe dizziness, fainting, and hypotension.
In case of overdose, seek immediate medical attention.

Therapeutic Class:
Alpha-1 Adrenergic Receptor Blocker

Storage Conditions:
Store at room temperature (15–30°C), away from moisture and direct sunlight.
Keep out of reach of children.